{"id":1038,"date":"2026-04-07T09:29:10","date_gmt":"2026-04-07T09:29:10","guid":{"rendered":"https:\/\/accelerator.high-tech.nrw\/?p=1038"},"modified":"2026-07-21T14:16:28","modified_gmt":"2026-07-21T14:16:28","slug":"lipofluddy-eng","status":"publish","type":"post","link":"https:\/\/accelerator.high-tech.nrw\/en\/batch-8-eng\/lipofluddy-eng\/","title":{"rendered":"LipoFluddy"},"content":{"rendered":"\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9a3f3cf4 wp-block-columns-is-layout-flex\" style=\"margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--80);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--80)\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"612\" height=\"428\" src=\"https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/03\/LipoFluddy.png\" alt=\"\" class=\"wp-image-396\" style=\"aspect-ratio:1.568158540436078;width:287px;height:auto\" srcset=\"https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/03\/LipoFluddy.png 612w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/03\/LipoFluddy-300x210.png 300w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/03\/LipoFluddy-500x350.png 500w\" sizes=\"auto, (max-width: 612px) 100vw, 612px\" \/><\/figure>\n\n\n\n<div style=\"height:27px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-image aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-1024x768.jpeg\" alt=\"\" class=\"wp-image-975\" style=\"aspect-ratio:4\/3;object-fit:cover;width:360px;height:auto\" srcset=\"https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-1024x768.jpeg 1024w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-300x225.jpeg 300w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-768x576.jpeg 768w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-1536x1152.jpeg 1536w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-500x375.jpeg 500w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-800x600.jpeg 800w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1-1280x960.jpeg 1280w, https:\/\/accelerator.high-tech.nrw\/wp-content\/uploads\/2026\/04\/LipoFLUDDY_team_photo-1.jpeg 1600w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><figcaption class=\"wp-element-caption\">Team<\/figcaption><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-block-column-is-layout-flow\"><div class=\"taxonomy-category is-style-post-terms-1 is-style-post-terms-1--1 wp-block-post-terms\"><a href=\"https:\/\/accelerator.high-tech.nrw\/en\/category\/batch-8-eng\/\" rel=\"tag\">Batch #8<\/a><\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\"><strong>Lipo-FLUDDY<\/strong> is a transfer project from the University of Cologne that develops dual-fluorescence dyes that make lipophagy measurable in living cells. The dye works in microscopy, flow cytometry, and plate readers\u2014where lipophagy has often only been measured indirectly until now. This enables high-throughput screening for active substances against lipid metabolism disorders, such as fatty liver disease, where scalability, comparability, and quantification are important. The combination of pH-switchable and pH-stable fluorophores makes the method protein label-free and compatible with common laboratory platforms. <strong>Lipo-FLUDDY<\/strong> thus closes a measurement gap in cell biology \u2013 a key to faster, data-driven drug development for metabolic diseases.<\/p>\n<\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Lipo-FLUDDY is a transfer project from the University of Cologne that develops dual-fluorescence dyes that make lipophagy measurable in living cells. The dye works in microscopy, flow cytometry, and plate readers\u2014where lipophagy has often only been measured indirectly until now. This enables high-throughput screening for active substances against lipid metabolism disorders, such as fatty liver [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"single-2","format":"standard","meta":{"_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"categories":[73],"tags":[],"class_list":["post-1038","post","type-post","status-publish","format-standard","hentry","category-batch-8-eng"],"_links":{"self":[{"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/posts\/1038","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/comments?post=1038"}],"version-history":[{"count":1,"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/posts\/1038\/revisions"}],"predecessor-version":[{"id":1039,"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/posts\/1038\/revisions\/1039"}],"wp:attachment":[{"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/media?parent=1038"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/categories?post=1038"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/accelerator.high-tech.nrw\/en\/wp-json\/wp\/v2\/tags?post=1038"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}